The Proven Performers

Retinoids are the gold standard of anti-aging. They increase cell turnover, boost collagen production, and reduce fine lines. Start with retinol at 0.25 percent and build tolerance gradually.

Vitamin C in the form of L-ascorbic acid at 10 to 20 percent concentration is the best-proven antioxidant for brightening skin, fading dark spots, and protecting against environmental damage. It works best in serums applied in the morning under sunscreen.