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LESSON 5 · The Molecules of Life

The Chemistry Behind Lasting Love

Here is what neuroscience tells us about love's chemical picture:

  • Dopamine creates the euphoric rush of new love but naturally fades after 1-3 years
  • Serotonin drops during attraction, driving obsessive thinking about your partner
  • Norepinephrine causes the racing heart, sweaty palms, and dilated pupils
  • Oxytocin builds during physical touch, creating long-term bonding and trust
  • Vasopressin supports protectiveness and loyalty in long-term partnerships

The shift from passionate to companionate love is not love fading — it is your brain moving from dopamine-driven excitement to oxytocin-driven security.